| Date | Location | Result | |
| 11/10/18 | Crawfordsville, IN | Wabash College 24, DePauw 17 | Box score |
| 11/3/2018 | Greencastle, Indiana | DePauw 38, Kenyon 6 | Box score |
| 10/27/2018 | Meadville, PA | Allegheny 20, DePauw 19 | Box score |
| 10/20/2018 | Springfield, Ohio | Wittenberg 38, DePauw 23 | Box score |
| 10/13/2018 | Greencastle, Indiana | Denison 20, DePauw 12 | Box score |
| 10/6/2018 | Oberlin, Ohio | DePauw 28, Oberlin College 26 | Box score |
| 9/29/2018 | Greencastle, Ind. | DePauw 38, Ohio Wesleyan 17 | Box score |
| 9/22/2018 | Wooster, Ohio | College of Wooster 24, DePauw 21 | Box score |
| 9/15/2018 | Greencastle, Ind. | DePauw 45, Hiram 7 | Box score |
| 9/8/2018 | Greencastle, Ind. | Central (Iowa) 16, DePauw 10 | Box score |